|Full Name||budding uninhibited by benzimidazoles 1 homolog beta (yeast)|
|Product Description||Rabbit polyclonal antibody to BUB1B (BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast))|
|Background||This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq]|
|Synonyms||BUB1beta antibody, BUBR1 antibody, Bub1A antibody, MAD3L antibody, SSK1 antibody, hBUBR1 antibody, BUB1B antibody, mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody, mitotic checkpoint kinase MAD3L antibody, MAD3/BUB1-related protein kinase antibody, budding uninhibited by benzimidazoles 1 homolog beta (yeast) antibody|
|Cellular Localization||Cytoplasm , Nucleus , Kinetochore |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human BUB1B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (87%)|