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1 .GTX21991 Bacillus anthracis protective antigen antibody [BAP0104]

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Bacillus anthracis protective antigen antibody [BAP0104]


  • Host / ClonalityMouse Monoclonal
  • Clone NameBAP0104
  • ApplicationsELISA
Cat No: GTX21991
Package Price Qty
100 μgUSD 219.00
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  • Datasheet
  • Application Information: Bacillus anthracis protective antigen antibody [BAP0104]

Catalog Number GTX21991
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Product Name Bacillus anthracis protective antigen antibody [BAP0104]
See all Bacillus anthracis protective antigen products
ApplicationsELISA
Application NoteELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
Concentration2 mg/ml (Please refer to the vial label for the specific concentration)
PurificationProtein G purified
Purification NotePurity is tested by electrophoresis.

  • Specifications: Bacillus anthracis protective antigen antibody [BAP0104]

BackgroundProtective antigen (PA) is one of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these is toxic by itself. PA+LF forms the lethal toxin (LeTx); PA+EF forms the edema toxin (EdTx). PA-63 forms heptamers and this oligomerization is required for LF or EF binding. Once activated, at low pH, the heptamer undergoes conformational changes and converts from prepore to pore inserted in the membrane, forming cation-selective channels.
Synonyms2820165, Bacillus anthracis protective antigen, pagA
SpecificityThis antibody is not cross-reacting with lethal factor antigen of B. antracis, Y.Pestis, F. Tularensis, and Toxoplasma gondii.
HostMouse
ClonalityMonoclonal
Clone NameBAP0104
IsotypeIgG2b
ImmunogenHighly purified protective antigen of Bacillus anthracis.
ConjugationUnconjugated

  • Storage Conditions: Bacillus anthracis protective antigen antibody [BAP0104]

Storage BufferPreservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Infectious Disease > Bacteria / Worm / Fungus > bacillus anthracis (Anthrax)
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Bacillus anthracis protective antigen antibody [BAP0104] validated data
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