|Full Name||BCL2-associated agonist of cell death|
|Product Description||Rabbit Polyclonal antibody to Bad (BCL2-associated agonist of cell death)|
|Background||The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq]|
|Synonyms||BAD Antibody , BBC2 Antibody , BCL2L8 Antibody , BCL2-associated agonist of cell death Antibody|
|Cellular Localization||Mitochondrion outer membrane , Cytoplasm|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Bad. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (86%), Chimpanzee (100%)|