|Full Name||BCL2-associated athanogene|
|Product Description||Rabbit polyclonal antibody to Bag1 (BCL2-associated athanogene)|
|Background||The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites. [provided by RefSeq]|
|Synonyms||HAP antibody, RAP46 antibody, BAG1 antibody, Bcl-2 associating athanogene-1 protein antibody, Bcl-2-binding protein antibody, BAG-1 antibody, BAG family molecular chaperone regulator 1 antibody, glucocortoid receptor-associated protein RAP46 antibody, "receptor-associated protein, 46-KD antibody", BCL2-associated athanogene antibody|
|Cellular Localization||Isoform 2: Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Bag1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (82%), Rat (81%), Pig (87%), Bovine (91%)|