|Full Name||B-cell CLL/lymphoma 2|
|Product Description||Rabbit Polyclonal antibody to BCL2 (B-cell CLL/lymphoma 2)|
|Background||This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq]|
|Synonyms||Bcl-2 antibody, BCL2 antibody, protein phosphatase 1, regulatory subunit 50 antibody, apoptosis regulator Bcl-2 antibody, B-cell CLL/lymphoma 2 antibody|
|Cellular Localization||Mitochondrion outer membrane , Nucleus membrane , Endoplasmic reticulum membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Bcl-2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Dog (100%), Cat (100%)|