|Product Description||Rabbit Polyclonal antibody to Biglycan (biglycan)|
|Background||The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival. This gene is a candidate gene for the Happle syndrome. [provided by RefSeq]|
|Synonyms||DSPG1 antibody, PG-S1 antibody, PGI antibody, SLRR1A antibody, BGN antibody, bone/cartilage proteoglycan I antibody, dermatan sulphate proteoglycan I antibody, biglycan proteoglycan antibody, small leucine-rich protein 1A antibody, bone/cartilage proteoglycan-I antibody, biglycan antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Biglycan. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Rabbit, Sheep, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Xenopus laevis (80%), Dog (97%), Rabbit (97%), Sheep (98%), Bovine (98%)|