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1 .GTX14391 Bradykinin antibody

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Bradykinin antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsELISA
  • Species reactivityHuman
Cat No: GTX14391
Package Price Qty
250 μlUSD 319.00
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  • Datasheet
  • Application Information: Bradykinin antibody

Catalog Number GTX14391
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Product Name Bradykinin antibody
See all Kininogen 1 products
ApplicationsELISA
Application NoteELISA: Use at a dilution of 1/250. Optimal dilutions/concentrations should be determined by the end user.
Form SuppliedLiquid
Concentrationantiserum
PurificationWhole antiserum

  • Specifications: Bradykinin antibody

Full Namekininogen 1
BackgroundBradykinin is a nine-amino-acid vasoactive peptide which elicits numerous physiologic responses such as vasodilation, smooth muscle spasm and pain. Bradykinin is one of a family of such peptides called the kinins. These kinins are generated by proteolysis of high-molecular-weight precursors called kininogens upon activation by pathophysiologic conditions such as inflammation or allergy. The physiological actions of these kinins are brought about through their interaction with transmembrane receptors. There are two distinct bradykinin receptor subtypes; B1 and B2, both of which appear to be coupled to G-proteins. The B2 receptor subtype is found in healthy smooth muscle cells and neurons, whereas the B1 receptors are only detected following tissue injury. The B2 receptor is similar in structure to other seven-helix G-protein-coupled receptors. Bradykinin has relatively low affinity for B1 receptors, interacting primarily with the B2 receptor through which several second messenger systems are stimulated, including inositol phospholipid hydrolysis, arachidonic acid metabolism, tyrosine phosphorylation, and membrane depolarization and hyperpolarization.
Synonyms3827, kininogen, KNG, P01042, BDK, Bradykinin, KNG1, 228960
Cellular LocalizationSecreted
SpecificityBradykinin: 100%
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenFull length protein (Human) conjugated to BSA.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: Bradykinin antibody

Storage BufferNeat serum without preservatives.
Storage InstructionKeep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cell Biology > Cell adhesion > Regulation > Negative regulation
  • Disease Related > Cardiovascular > Heart > Heart disease
  • Disease Related > Cardiovascular > Vessels
  • Disease Related > Diabetes
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Bradykinin antibody validated data
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All products are for research use only—Not for use in diagnostic procedures.