|Product Description||Mouse Monoclonal antibody [GT1489] to C-peptide (insulin)|
|Background||After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]|
|Synonyms||INS Antibody , IDDM2 Antibody , ILPR Antibody , insulin Antibody , IRDN Antibody , MODY10 Antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human insulin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%)|