|Full Name||carbonic anhydrase XI|
|Product Description||Rabbit polyclonal antibody to CA11 (carbonic anhydrase XI)|
|Background|| Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq]|
|Synonyms||CARPX1 antibody, CA11 antibody, CARP-2 antibody, carbonic anhydrase-related protein 2 antibody, CARP XI antibody, carbonic anhydrase-related protein XI antibody, carbonic anhydrase-related protein 11 antibody, CA-XI antibody, CA-RP II antibody, carbonic anhydrase XI antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CA11. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Sheep, Bovine|
|Predict Reactivity Note||Pig (97%), Sheep (97%), Bovine (97%)|