Full Name | phosphatidylinositol binding clathrin assembly protein |
Background | Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. |
Synonyms | CALM antibody, CLTH antibody, LAP antibody, PICALM antibody, phosphatidylinositol-binding clathrin assembly protein antibody, clathrin assembly lymphoid myeloid leukemia protein antibody, phosphatidylinositol binding clathrin assembly protein antibody |
Cellular Localization | Membrane , clathrin-coated pit , Golgi apparatus , Cytoplasmic vesicle , clathrin-coated vesicle |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the center region of human CALM. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Mouse, Rat, Pig, Rhesus Monkey, Bovine |
Predict Reactivity Note | Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%) |
Conjugation | Unconjugated |