|Product Description||Rabbit polyclonal antibody to CARKL (sedoheptulokinase)|
|Background||The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq]|
|Synonyms||CARKL antibody, FLJ32478 antibody, SHK antibody, SHPK antibody, carbohydrate kinase-like protein antibody, sedoheptulokinase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CARKL. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (91%), Rat (92%), Bovine (90%)|