|Full Name||carnitine O-acetyltransferase|
|Product Description||Rabbit Polyclonal antibody to CAT1 (carnitine O-acetyltransferase)|
|Background||Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The alternatively splicing of this gene results in three distinct isoforms, one of which contains an N-terminial mitochondrial transit peptide, and has been shown to be located in mitochondria. [provided by RefSeq]|
|Synonyms||CAT1 antibody, CRAT antibody, carnitine O-acetyltransferase antibody, CAT antibody, carnitine acetylase antibody, carnitine acetyltransferase antibody|
|Cellular Localization||Endoplasmic reticulum , Peroxisome , Mitochondrion inner membrane; Peripheral membrane protein; Matrix side , Endoplasmic reticulum , Peroxisome , Mitochondrion inner membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CAT1. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (90%), Pig (92%), Rhesus Monkey (98%), Bovine (90%)|