|Full Name||Cas-Br-M (murine) ecotropic retroviral transforming sequence|
|Product Description||Goat polyclonal antibody to CBL|
|Background||Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling. |
|Synonyms||CBL2, CasBrM ecotropic retroviral transforming sequence (Oncogene CBL2), RNF55, CBL, Cas-Br-M (murine) ecotropi, C-CBL, Cas-Br-M ecotropic retroviral transforming sequence (Oncogene CBL2), CasBrM (murine) ecotropic retroviral transforming sequence, CasBrM (murine) ecotropi, CCBL, C CBL, Cas Br M (murine) ecotropi|
|Specificity||This antibody is specific for CBL.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Dog, Pig, Bovine|