|Product Description||Rabbit Polyclonal antibody to CBS (cystathionine-beta-synthase)|
|Background||The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]|
|Synonyms||HIP4 antibody, CBS antibody, serine sulfhydrase antibody, beta-thionase antibody, cystathionine beta-synthase antibody, methylcysteine synthase antibody, cystathionine-beta-synthase antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CBS. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Rabbit, Bovine|
|Predict Reactivity Note||Rat (94%), Xenopus laevis (93%), Rabbit (95%), Bovine (94%)|