|Full Name||chromobox homolog 1|
|Product Description||Rabbit Polyclonal antibody to CBX1 / HP1 beta (chromobox homolog 1 (HP1 beta homolog Drosophila ))|
|Background||This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||CBX antibody, HP1-BETA antibody, HP1Hs-beta antibody, HP1Hsbeta antibody, M31 antibody, MOD1 antibody, p25beta antibody, CBX1 antibody, chromobox homolog 1 (HP1 beta homolog Drosophila ) antibody, chromobox protein homolog 1 antibody, heterochromatin protein 1-beta antibody, heterochromatin protein 1 homolog beta antibody, heterochromatin protein p25 beta antibody, modifier 1 protein antibody, HP1 beta homolog antibody, chromobox homolog 1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CBX1 / HP1 beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Xenopus laevis (80%), Chicken (83%), Chimpanzee (100%), Bovine (100%)|