|Full Name||cyclin D-type binding-protein 1|
|Product Description||Rabbit Polyclonal antibody to CCNDBP1 (cyclin D-type binding-protein 1)|
|Background||This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported. [provided by RefSeq]|
|Synonyms||DIP1 antibody, GCIP antibody, CCNDBP1 antibody, grap2 and cyclin-D-interacting protein antibody, cyclin-D1-binding protein 1 antibody, human homolog of Maid antibody, cyclin D-type binding-protein 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCNDBP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (83%)|