CD169 antibody [7-239] (Low endotoxin, azide free)
|Applications||FACS, IHC-Fr, IP, Functional Assay|
| Flow cytometry/FACS||Assay-dependent dilution
|IHC (Frozen sections)||1/100*
| Immunoprecipitation||Assay-dependent dilution
| Functional Assay||Assay-dependent dilution
Flow cytometry/FACS : Use 10μl of the suggested working dilution to label 106 cells in 100μl.Not tested in other applications.
IHC (Frozen sections) : The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. We recommends the use of acetone fixation for frozen sections.
*Optimal dilutions/concentrations should be determined by the researcher.
(Please refer to the vial label for the specific concentration)|
|Purification||Protein G purified|
|Purification Note||From tissue culture supernatant|
|Full Name||sialic acid binding Ig like lectin 1|
|Product Description||Mouse monoclonal antibody [7-239] to CD169|
|Background||This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]|
|Synonyms||SIGLEC-1 Antibody , SIGLEC1 Antibody , DJ1009E24.1 Antibody , SN Antibody|
|Immunogen||Human Rhinovirus (HRV14) treated monocyte-derived dendritic cells.|