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1 .GTX18229 CD19 antibody [LT19] (PE)

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CD19 antibody [LT19] (PE)


  • Host / ClonalityMouse Monoclonal
  • Clone NameLT19
  • ApplicationsFACS
  • Species reactivityHuman
Cat No: GTX18229
Package Price Qty
100 testUSD 319.00
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  • Anti-CD19 antibody [LT19] (PE) used in Flow cytometry/FACS. GTX18229
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  • Datasheet
  • Application Information: CD19 antibody [LT19] (PE)

Catalog Number GTX18229
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Product Name CD19 antibody [LT19] (PE)
See all CD19 products
ApplicationsFACS
Application NoteFACS: Use 20μl for 100μl human whole blood cells. Optimal dilutions/concentrations should be determined by the end user.
Form SuppliedLiquid
PurificationProtein G purified
Purification NoteConjugate purified by size-exclusion chromatography

  • Specifications: CD19 antibody [LT19] (PE)

Full NameCD19 molecule
BackgroundCD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10% of normal human peripheral blood cells and approximately 60% of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12% of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation. It is expressed in all B cell precursor leukemias. Recent cDNA cloning of CD19 has shown significant homology in the cytoplasmic domain of CD19 with the int1 oncogene.
SynonymsB4, MGC12802, CD19, 107265, 930, P15391, CVID3
Cellular LocalizationType I membrane protein.
HostMouse
ClonalityMonoclonal
Clone NameLT19
IsotypeIgG1
ImmunogenHuman B lymphoblast cell line Daudi.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationPhycoerythrin (PE)

  • Storage Conditions: CD19 antibody [LT19] (PE)

Storage BufferPreservative: 15mM Sodium Azide. Constituents: PBS, BSA. pH 7.4
Storage InstructionKeep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Tumor biomarkers
  • Immunology > Autoimmunity > Autoimmune diseases > Crohn Disease
  • Immunology > Autoimmunity > Autoimmune diseases > Rheumatoid Arthritis
  • Immunology > CD marker
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CD19 antibody [LT19] (PE) validated data
  • Anti-CD19 antibody [LT19] (PE) used in Flow cytometry/FACS. GTX18229
    • GTX18229 FACS Image
      Surface staining of human peripheral blood cells with anti-human CD19 [LT19]: APC (GTX18224)
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  • Anti-CD19 antibody [LT19] (PE) used in Flow cytometry/FACS. GTX18229
    • GTX18229 FACS Image
      Surface staining of human peripheral blood cells with anti-human CD19 [LT19]: APC (GTX18224)
      Top
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