CD1B antibody [N2C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||CD1b molecule|
|Product Description||Rabbit polyclonal antibody to CD1B (CD1B molecule)|
|Background||This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq]|
|Synonyms||CD1 antibody, CD1A antibody, MGC125990 antibody, MGC125991 antibody, R1 antibody, CD1B antibody, T-cell surface glycoprotein CD1b antibody, "CD1B antigen, b polypeptide antibody", cortical thymocyte antigen CD1B antibody, differentiation antigen CD1-alpha-3 antibody, CD1b molecule antibody|
|Cellular Localization||Cell membrane , Endosome membrane , Lysosome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CD1B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (95%)|