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1 .GTX114015 CD22 antibody [C2C3], C-term

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CD22 antibody [C2C3], C-term


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsWB
  • Species reactivityHuman
Cat No: GTX114015
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
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  • Anti-CD22 antibody [C2C3], C-term used in Western Blot (WB). GTX114015
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  • Application Information: CD22 antibody [C2C3], C-term

Catalog Number GTX114015
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Product Name CD22 antibody [C2C3], C-term
See all CD22 products
ApplicationsWB
Application Note
Suggested dilutionReference
Western Blot (WB)1:500-1:3000*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size95 kDa (note) IsoForm (5)
Positive ControlsRaji
Form SuppliedLiquid
Concentration0.79 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography.

  • Specifications: CD22 antibody [C2C3], C-term

Full NameCD22 molecule
BackgroundMediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
SynonymsFLJ22814 antibody, MGC130020 antibody, SIGLEC-2 antibody, SIGLEC2 antibody, CD22 antibody, B-lymphocyte cell adhesion molecule antibody, T-cell surface antigen Leu-14 antibody, sialic acid-binding Ig-like lectin 2 antibody, CD22 antigen antibody, BL-CAM antibody, sialic acid binding Ig-like lectin 2 antibody, B-cell receptor CD22 antibody, CD22 molecule antibody
Cellular LocalizationCell membrane
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant protein encompassing a sequence within the C-terminus region of human CD22. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: CD22 antibody [C2C3], C-term

Storage Buffer0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Tumor biomarkers
  • Immunology > CD marker
  • Signal Transduction > ECM/Cytoskeleton > Cell Adhesion
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CD22 antibody [C2C3], C-term validated data
  • Anti-CD22 antibody [C2C3], C-term used in Western Blot (WB). GTX114015
    • GTX114015 WB Image
      Sample (30 ug of whole cell lysate)
      A: Raji
      7.5% SDS PAGE
      GTX114015 diluted at 1:1000
      Top
  • Anti-CD22 antibody [C2C3], C-term used in Western Blot (WB). GTX114015
    • GTX114015 WB Image
      Sample (30 ug of whole cell lysate)
      A: Raji
      7.5% SDS PAGE
      GTX114015 diluted at 1:1000
      Top
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Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensCD22933Q0EAF5, Q32M46, P20273107266NP_00126534675.37
Homo sapiensCD22933Q0EAF5, Q32M46, P20273107266BC109306AAI0930775.37
Homo sapiensCD22933Q0EAF5, Q32M46, P20273107266NM_001185099NP_00117202885.69
Homo sapiensCD22933Q0EAF5, Q32M46, P20273107266NM_001185101NP_00117203075.81
Homo sapiensCD22933Q0EAF5, Q32M46, P20273107266NM_001771NP_00176295.37
    *MSDS
    MSDS-Glycerol.pdf
    MSDS-Thimerosal.pdf

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