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CD24 antibody [SN3]

Anti-CD24 antibody [SN3] used in Flow cytometry (FACS). GTX74945

Cat. No. GTX74945

Reference 9

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SN3

Isotype

 IgG1

Application

 WB, IHC-Fr, FACS

Reactivity

 Human, Mouse, Chimpanzee
Package
200 μg ($459)
See all CD24 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
FACS 1/50-1/100

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.
Not tested in other applications.

Calculated MW

8 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Glycoproteins purified from human NALM-1 cell line.

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_376539

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD24 molecule , CD24A

Background

This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Database

Research Area

DATA IMAGES

Anti-CD24 antibody [SN3] used in Flow cytometry (FACS). GTX74945

GTX74945 FACS Image

FACS analysis of human peripheral blood granulocytes using GTX74945 CD24 antibody [SN3].

REFERENCE

Clone Reference

X Wang et al. Cell Metab 2022; 34 (8):1088-1103 CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder
Application : WB
Reactivity : Mouse
Ricci F et al. Cell Cycle 2012; 11 (10):1966-76 Ovarian carcinoma tumor-initiating cells have a mesenchymal phenotype.
Angelotti ML et al. Stem Cells 2012; 30 (8):1714-25 Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury.
Jiang W et al. Stem Cells 2011; 29 (4):609-17 CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells.
Lasagni L et al. Stem Cells 2010; 28 (9):1674-85 Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459