|Full Name||CD3e molecule, epsilon (CD3-TCR complex)|
|Product Description||Rabbit polyclonal antibody to CD3E (CD3E molecule, epsilon (CD3-TCR complex))|
|Background||The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq]|
|Synonyms||FLJ18683 antibody, T3E antibody, TCRE antibody, CD3E antibody, "T-cell antigen receptor complex, epsilon subunit of T3 antibody", CD3-epsilon antibody, "CD3e antigen, epsilon polypeptide (TiT3 complex) antibody", T-cell surface antigen T3/Leu-4 epsilon chain antibody, T-cell surface glycoprotein CD3 epsilon chain antibody, "CD3e molecule, epsilon (CD3-TCR complex) antibody"|
|Cellular Localization||Membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD3 epsilon. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Cat, Pig, Rabbit, Sheep, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (87%), Dog (87%), Cat (87%), Pig (100%), Rabbit (93%), Sheep (87%), Bovine (80%)|