CD36 antibody [SMØ] (Azide free)
|Applications||FACS, IHC-Fr, Functional Assay|
| IHC (Frozen sections)||Assay-dependent dilution
| Functional Assay||Assay-dependent dilution
Flow cytometry/FACS : Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.Not tested in other applications.
Functional Assay : Mouse anti Human CD36 antibody, clone SMØ is also reported to block interaction of oxidised low-density lipoprotein (OXLDL) with CD36 (Sugihara et al.1992).
*Optimal dilutions/concentrations should be determined by the researcher.
(Please refer to the vial label for the specific concentration)|
|Purification||Ammonium sulphate precipitation|
|Purification Note||From tissue culture supernatant|
|Full Name||CD36 molecule|
|Product Description||Mouse monoclonal antibody [SM0] to CD36|
|Background||The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]|
|Synonyms||GPIV Antibody , FAT Antibody , CHDS7 Antibody , GP3B Antibody , SCARB3 Antibody , PASIV Antibody , BDPLT10 Antibody , GP4 Antibody|
|Immunogen||Human tonsil cells and peripheral blood mononuclear cells.|