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  • CD40L / CD154 antibody [5F3]

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1 .GTX13546 CD40L / CD154 antibody [5F3]

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CD40L / CD154 antibody [5F3]


  • Host / ClonalityMouse Monoclonal
  • Clone Name5F3
  • ApplicationsFACS
  • Species reactivityHuman
Cat No: GTX13546
Package Price Qty
50 μgUSD 319.00
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  • Anti-CD40L / CD154 antibody [5F3] used in Flow cytometry/FACS. GTX13546
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  • Datasheet
  • Application Information: CD40L / CD154 antibody [5F3]

Catalog Number GTX13546
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Product Name CD40L / CD154 antibody [5F3]
See all CD40L / CD154 products
ApplicationsFACS
Application NoteFACS: Use at a concentration of 5 - 10 μg/ml. Optimal dilutions/concentrations should be determined by the end user.
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationProtein A purified
Purification NoteThis antibody is affinity purified.

  • Specifications: CD40L / CD154 antibody [5F3]

Full NameCD40 ligand
BackgroundCD40 ligand (CD40L), also known as CD154, gp39 and TRAP, is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X-linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
SynonymsTRAP, IMD3, CD40L, 300386, 959, IGM, TNFSF5, HIGM1, CD40LG, CD154, gp39, TBAM, hCD40L, P29965, T-BAM, T BAM
Cellular LocalizationType II membrane protein. Also exists as an extracellular soluble form.
HostMouse
ClonalityMonoclonal
Clone Name5F3
IsotypeIgG1
ImmunogenHuman CD40L (CD154) transfected 300-19 cell (Mouse pre-B cell line).
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: CD40L / CD154 antibody [5F3]

Storage BufferPreservative: NoneConstituents: 1% Sucrose, PBS. pH 7.2.
Storage InstructionKeep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Apoptosis > Anti-apoptosis
  • Cell Biology > Apoptosis > Anti-apoptosis
  • Cell Biology > Cell adhesion > Cell-cell adhesion > Leukocyte
  • Disease Related > Alzheimer's disease
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CD40L / CD154 antibody [5F3] validated data
  • Anti-CD40L / CD154 antibody [5F3] used in Flow cytometry/FACS. GTX13546
    • GTX13546 FACS Image
      Flow cytometric analysis of CD154 expression on cells transfected with CD154 vector. Cells were stained with isotype control (open histogram) or CD40L (CD154) mAb (5F3) (shaded histogram).
      Top
  • Anti-CD40L / CD154 antibody [5F3] used in Flow cytometry/FACS. GTX13546
    • GTX13546 FACS Image
      Flow cytometric analysis of CD154 expression on cells transfected with CD154 vector. Cells were stained with isotype control (open histogram) or CD40L (CD154) mAb (5F3) (shaded histogram).
      Top
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