| Full Name | CD63 molecule |
| Background | CD63 is intracellular lysosomal/endosomal/granule protein that is translocated to cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker). CD63 is also expressed on monocytes/macrophages and endothelium. Its cellular function has not been exactly elucidated. CD63 is thought to be associated with the early stages of melanoma tumor progression (in regulation of motility and adhesion of melanoma cells). |
| Synonyms | LAMP-3, ME491, MLA1, OMA81H, TSPAN30 |
| Specificity | The antibody MEM-259 reacts with CD63 (Melanoma 1 antigen), a 40-60 kDa glycoprotein (tetraspans family, TM4SF). CD63 is translocated to the cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker); it is also expressed on monocytes/macrophages and endothelium. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | MEM-259 |
| Isotype | IgG1 |
| Immunogen | Tissue / cell preparation (Human). (T cell line HPB-ALL) |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |