|Full Name||CD68 molecule|
|Product Description||Rabbit Polyclonal antibody to CD68 (macrosialin)|
|Background||This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq]|
|Synonyms||DKFZp686M18236 antibody, GP110 antibody, SCARD1 antibody, CD68 antibody, macrosialin antibody, "scavenger receptor class D, member 1 antibody", macrophage antigen CD68 antibody, CD68 antigen antibody, CD68 molecule antibody|
|Cellular Localization||Isoform Short: Cell membrane , Isoform Long: Endosome membrane , Lysosome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CD68. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%)|