|Applications||Blocking, FACS, ICC/IF, IHC-P, WB|
Not tested in other applications.
| Blocking||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||26 kDa (note)
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||CD81 molecule|
|Product Description||Rabbit Polyclonal antibody to CD81 (CD81 molecule)|
|Background||The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq]|
|Synonyms||CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 antibody, CD81 antigen antibody, 26 kDa cell surface protein TAPA-1 antibody, tetraspanin-28 antibody, CD81 antigen (target of antiproliferative antibody 1) antibody, tspan-28 antibody, CD81 molecule antibody|
|Cellular Localization||Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CD81. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (86%), Pig (92%), Sheep (92%), Rhesus Monkey (96%), Chimpanzee (100%), Bovine (89%)|