|Full Name||cell division cycle 25 homolog A (S. pombe)|
|Product Description||Rabbit Polyclonal antibody to CDC25A (cell division cycle 25 homolog A (S. pombe))|
|Background||CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||CDC25A2 antibody, CDC25A antibody, cell division cycle 25A antibody, dual specificity phosphatase CDC25A antibody, CDC25A2-CAG isoform antibody, M-phase inducer phosphatase 1 antibody, cell division cycle 25 homolog A (S. pombe) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human CDC25A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Dog (89%), Bovine (90%)|