|Full Name||cell division cycle 25 homolog B (S. pombe)|
|Product Description||Rabbit Polyclonal antibody to CDC25B (cell division cycle 25 homolog B (S. pombe))|
|Background||CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq]|
|Synonyms||CDC25B antibody, M-phase inducer phosphatase 2 antibody, dual specificity phosphatase Cdc25B antibody, cell division cycle 25B antibody, cell division cycle 25 homolog B (S. pombe) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human CDC25B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (92%), Pig (93%), Bovine (93%)|