|Full Name||cell division cycle 27 homolog (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to CDC27 (cell division cycle 27 homolog (S. cerevisiae))|
|Background||The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||ANAPC3 antibody, APC3 antibody, CDC27Hs antibody, D0S1430E antibody, D17S978E antibody, HNUC antibody, NUC2 antibody, CDC27 antibody, anaphase-promoting complex subunit 3 antibody, cell division cycle protein 27 homolog antibody, CDC27 homolog antibody, "anaphase-promoting complex, protein 3 antibody", anaphase promoting complex subunit 3 antibody, nuc2 homolog antibody, H-NUC antibody, cell division cycle 27 homolog (S. cerevisiae) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDC27. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (91%), Rat (92%), Xenopus laevis (80%), Chicken (87%), Bovine (96%)|