|Full Name||CDC42 effector protein (Rho GTPase binding) 2|
|Product Description||Rabbit Polyclonal antibody to CDC42EP2 (CDC42 effector protein (Rho GTPase binding) 2)|
|Background||CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq]|
|Synonyms||BORG1 antibody, CEP2 antibody, CDC42EP2 antibody, CRIB-containing BOGR1 protein antibody, cdc42 effector protein 2 antibody, binder of Rho GTPases 1 antibody, CDC42 effector protein (Rho GTPase binding) 2 antibody|
|Cellular Localization||Endomembrane system , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rat (89%), Rhesus Monkey (99%), Bovine (88%)|