|Full Name||cell division cycle 45 homolog (S. cerevisiae)|
|Product Description||Rabbit Polyclonal antibody to CDC45L (CDC45 cell division cycle 45-like (S. cerevisiae))|
|Background||The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. [provided by RefSeq]|
|Synonyms||CDC45L antibody, CDC45L2 antibody, PORC-PI-1 antibody, CDC45 antibody, CDC45-related protein antibody, cell division cycle 45-like 2 antibody, human CDC45 antibody, cell division control protein 45 homolog antibody, CDC45 cell division cycle 45 homolog antibody, cell division cycle 45 homolog (S. cerevisiae) antibody|
|Cellular Localization||Cytoplasm , Nucleus|
|Specificity||Knockdown/Knockout validation was supported by customer review data.|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDC45L. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (92%), Bovine (90%)|