|Full Name||cadherin 11, type 2, OB-cadherin (osteoblast)|
|Product Description||Rabbit Polyclonal antibody to OB-cadherin (cadherin 11, type 2, OB-cadherin (osteoblast))|
|Background||This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq]|
|Synonyms||CAD11 antibody, CDHOB antibody, OB antibody, OSF-4 antibody, CDH11 antibody, cadherin-11 antibody, "cadherin 11, type 2, OB-cadherin (osteoblast) antibody"|
|Cellular Localization||Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDH11. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (82%), Xenopus laevis (92%), Pig (99%), Chicken (96%), Rhesus Monkey (99%), Bovine (100%)|