|Full Name||cyclin-dependent kinase 2|
|Product Description||Rabbit polyclonal antibody to CDK2 (cyclin-dependent kinase 2)|
|Background||The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]|
|Synonyms||p33(CDK2) antibody, CDK2 antibody, cdc2-related protein kinase antibody, cell devision kinase 2 antibody, cyclin-dependent kinase 2 antibody, p33 protein kinase antibody, cell division protein kinase 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDK2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Sheep, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Zebrafish (92%), Pig (98%), Chicken (95%), Sheep (98%), Bovine (98%)|