CDK5 antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||33 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , Jurkat , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cyclin-dependent kinase 5|
|Product Description||Rabbit Polyclonal antibody to CDK5 (cyclin-dependent kinase 5)|
|Background||Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.|
|Synonyms||PSSALRE antibody, CDK5 antibody, tau protein kinase II catalytic subunit antibody, cyclin-dependent kinase 5 antibody, protein kinase CDK5 splicing antibody, TPKII catalytic subunit antibody, cell division protein kinase 5 antibody, serine/threonine-protein kinase PSSALRE antibody|
|Cellular Localization||Cytoplasm , Cell projection , lamellipodium , growth cone |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CDK5. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%)|