Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||39 kDa (note)
|Positive Controls||HeLa , HepG2 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cyclin-dependent kinase 7|
|Product Description||Rabbit Polyclonal antibody to CDK7 (cyclin-dependent kinase 7)|
|Background||The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq]|
|Synonyms||CAK1 antibody, CDKN7 antibody, MO15 antibody, STK1 antibody, p39MO15 antibody, CDK7 antibody, TFIIH basal transcription factor complex kinase subunit antibody, cell division protein kinase 7 antibody, homolog of Xenopus MO15 Cdk-activating kinase antibody, kinase subunit of CAK antibody, CAK antibody, protein kinase antibody, p39 Mo15 antibody, serine/threonine-protein kinase 1 antibody, serine/threonine protein kinase MO15 antibody, serine/threonine kinase stk1 antibody, 39 KDa protein kinase antibody, cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) antibody, serine/threonine protein kinase 1 antibody, CDK-activating kinase 1 antibody, cyclin-dependent kinase 7 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDK7. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (84%), Xenopus laevis (86%), Pig (97%), Rhesus Monkey (99%), Bovine (96%)|