|Full Name||cyclin-dependent kinase 9|
|Product Description||Rabbit Polyclonal antibody to CDK9 (cyclin-dependent kinase 9)|
|Background||The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq]|
|Synonyms||C-2k antibody, CDC2L4 antibody, CTK1 antibody, PITALRE antibody, TAK antibody, CDK9 antibody, serine/threonine-protein kinase PITALRE antibody, cyclin-dependent kinase 9 antibody, serine/threonine protein kinase PITALRE antibody, CDC2-related kinase antibody, cell division cycle 2-like protein kinase 4 antibody, cell division protein kinase 9 antibody, tat-associated kinase complex catalytic subunit antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDK9. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (87%), Xenopus laevis (85%), Pig (98%), Chicken (87%), Rhesus Monkey (100%), Bovine (98%)|