|Full Name||CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1|
|Product Description||Rabbit Polyclonal antibody to CDS1 (CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1)|
|Background||Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq]|
|Synonyms||CDS antibody, CDS1 antibody, phosphatidate cytidylyltransferase 1 antibody, CDP-DAG synthase 1 antibody, CDS 1 antibody, CDP-diglyceride synthetase 1 antibody, CDP-diglyceride pyrophosphorylase 1 antibody, CTP:phosphatidate cytidylyltransferase 1 antibody, CDP-diacylglycerol synthase 1 antibody, CDP-DG synthase 1 antibody, CDP-diglyceride synthase 1 antibody, CDP-DG synthetase 1 antibody, CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Multi-pass membrane protein , Endoplasmic reticulum membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CDS1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (96%), Pig (96%)|