|Full Name||centromere protein J|
|Product Description||Rabbit polyclonal antibody to CENPJ (centromere protein J)|
|Background||This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. [provided by RefSeq]|
|Synonyms||BM032 antibody, CPAP antibody, LAP antibody, LIP1 antibody, MCPH6 antibody, MGC131581 antibody, MGC131582 antibody, MGC142222 antibody, MGC142224 antibody, SASS4 antibody, SCKL4 antibody, Sas-4 antibody, CENPJ antibody, centrosomal P4.1-associated protein antibody, centromere protein J antibody, LAG-3-associated protein antibody, LYST-interacting protein 1 antibody, LYST-interacting protein LIP7 antibody, LYST-interacting protein LIP1 antibody|
|Cellular Localization||Centrosome , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CENPJ. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Chimpanzee|
|Predict Reactivity Note||Human (100%), Mouse (92%), Rat (93%), Chimpanzee (99%)|