|Full Name||cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)|
|Product Description||Rabbit Polyclonal antibody to CFTR (cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7))|
|Background||This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq]|
|Synonyms||CFTR/MRP Antibody , cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) Antibody , dJ760C5.1 Antibody , ABCC7 Antibody , CF Antibody , MRP7 Antibody , ABC35 Antibody , TNR-CFTR Antibody|
|Cellular Localization||Membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CFTR. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|