|Full Name||chromodomain helicase DNA binding protein 1-like|
|Product Description||Rabbit Polyclonal antibody to CHD1L (chromodomain helicase DNA binding protein 1-like)|
|Background||In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]|
|Synonyms||ALC1 antibody, CHDL antibody, FLJ22530 antibody, CHD1L antibody, amplified in liver cancer 1 antibody, chromodomain-helicase-DNA-binding protein 1-like antibody, amplified in liver cancer protein 1 antibody, chromodomain helicase DNA binding protein 1-like antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (88%), Bovine (93%)|