|Full Name||chromatin modifying protein 2A|
|Product Description||Rabbit Polyclonal antibody to CHMP2A (chromatin modifying protein 2A)|
|Background||CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]|
|Synonyms||BC-2 antibody, BC2 antibody, CHMP2 antibody, VPS2 antibody, VPS2A antibody, CHMP2A antibody, vacuolar protein sorting-associated protein 2-1 antibody, chromatin modifying protein 2A antibody, putative breast adenocarcinoma marker (32kD) antibody, putative breast adenocarcinoma marker BC-2 antibody, VPS2 homolog A antibody, hVps2-1 antibody, charged multivesicular body protein 2a antibody, vps2-1 antibody, chromatin-modifying protein 2a antibody|
|Cellular Localization||Late endosome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CHMP2A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (99%), Rat (99%), Xenopus laevis (82%), Rhesus Monkey (100%), Bovine (97%)|