|Full Name||chromatin modifying protein 4C|
|Product Description||Rabbit Polyclonal antibody to CHMP4C (chromatin modifying protein 4C)|
|Background||CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]|
|Synonyms||MGC22825 antibody, SNF7-3 antibody, Shax3 antibody, VPS32C antibody, CHMP4C antibody, vacuolar protein sorting-associated protein 32-3 antibody, chromatin modifying protein 4C antibody, chromatin-modifying protein 4c antibody, hVps32-3 antibody, hSnf7-3 antibody, vps32-3 antibody, Snf7 homologue associated with Alix 3 antibody, SNF7 homolog associated with Alix 3 antibody, charged multivesicular body protein 4c antibody|
|Cellular Localization||Cytoplasm , cytosol , Late endosome membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CHMP4C. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (91%), Pig (95%), Chicken (83%), Rhesus Monkey (99%), Bovine (91%)|