|Full Name||cell death-inducing DFFA-like effector a|
|Product Description||Rabbit Polyclonal antibody to CIDE A (cell death-inducing DFFA-like effector a)|
|Background||This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||CIDE-A antibody, CIDEA antibody, cell death activator CIDE-A antibody, cell death-inducing DFFA-like effector a antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CIDE A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (86%), Pig (82%), Bovine (83%)|