|Full Name||TRAF3 interacting protein 2|
|Product Description||Rabbit Polyclonal antibody to CIKS (TRAF3 interacting protein 2)|
|Background||This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq]|
|Synonyms||ACT1 antibody, C6orf2 antibody, C6orf4 antibody, C6orf5 antibody, C6orf6 antibody, CIKS antibody, DKFZp586G0522 antibody, MGC3581 antibody, TRAF3IP2 antibody, TRAF3-interacting protein 2 antibody, connection to IKK and SAPK/JNK antibody, adapter protein CIKS antibody, nuclear factor NF-kappa-B activator 1 antibody, NFkB-activating protein ACT1 antibody, TRAF3 interacting protein 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human CIKS. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (97%), Rabbit (97%), Rhesus Monkey (100%), Bovine (99%)|