|Full Name||creatine kinase, mitochondrial 2 (sarcomeric)|
|Product Description||Rabbit Polyclonal antibody to CKMT2 (creatine kinase, mitochondrial 2 (sarcomeric))|
|Background||Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||SMTCK antibody, CKMT2 antibody, sarcomeric mitochondrial creatine kinase antibody, S-MtCK antibody, basic-type mitochondrial creatine kinase antibody, "creatine kinase S-type, mitochondrial antibody", mib-CK antibody, "creatine kinase, mitochondrial 2 (sarcomeric) antibody"|
|Cellular Localization||Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human CKMT2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Rat (100%), Dog (99%), Pig (100%), Rabbit (98%), Chicken (92%), Bovine (100%)|