|Full Name||component of oligomeric golgi complex 8|
|Product Description||Rabbit Polyclonal antibody to COG8 (component of oligomeric golgi complex 8)|
|Background||This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance. [provided by RefSeq]|
|Synonyms||CDG2H antibody, DOR1 antibody, FLJ22315 antibody, COG8 antibody, conserved oligomeric Golgi complex subunit 8 antibody, dependent on RIC1 antibody, conserved oligomeric golgi complex component 8 antibody, COG complex subunit 8 antibody, component of oligomeric golgi complex 8 antibody|
|Cellular Localization||Golgi apparatus membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human COG8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (91%), Bovine (90%)|