COL3A1 antibody [C2C3], C-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||139 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Neuro2A , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , rat liver , Mouse ESC , PC-12 , Rat2 , SK-N-SH , SK-N-AS|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||collagen, type III, alpha 1|
|Product Description||Rabbit Polyclonal antibody to COL3A1 (collagen, type III, alpha 1)|
|Background||This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]|
|Synonyms||EDS4A antibody, FLJ34534 antibody, COL3A1 antibody, alpha1 (III) collagen antibody, Ehlers-Danlos syndrome type IV, autosomal dominant antibody, collagen, fetal antibody, collagen alpha-1(III) chain antibody, collagen, type III, alpha 1 antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human COL3A1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (94%), Chicken (83%), Rhesus Monkey (98%), Bovine (94%)|