|Full Name||coatomer protein complex, subunit gamma|
|Product Description||Rabbit polyclonal antibody to COPG (coatomer protein complex, subunit gamma)|
|Background||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.|
|Synonyms||COPG1 antibody, FLJ21068 antibody, COPG antibody, gamma-coat protein antibody, "coatomer protein complex, subunit gamma 1 antibody", gamma-COP antibody, coat protein gamma-cop antibody, coatomer subunit gamma antibody, "coatomer protein complex, subunit gamma antibody"|
|Cellular Localization||Cytoplasm , Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side , Cytoplasmic vesicle , COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side , Cytoplasm , Golgi apparatus membrane , Cytoplasmic vesicle , COPI-coa|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human COPG. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Xenopus laevis (87%), Chicken (91%), Bovine (96%)|