|Full Name||COP9 signalosome subunit 8|
|Product Description||Rabbit Polyclonal antibody to COPS8 (COP9 signalosome subunit 8)|
|Background||The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]|
|Synonyms||CSN8 Antibody, COP9 Antibody, COP9 signalosome subunit 8 Antibody, SGN8 Antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human COPS8. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Bovine|
|Predict Reactivity Note||Rat (96%), Chicken (88%), Bovine (96%)|